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Myeloid cell expressed proprotein convertase FURIN attenuates inflammation
The proprotein convertase enzyme FURIN processes immature pro-proteins into functional end- products. FURIN is upregulated in activated immune cells and it regulates T-cell dependent peripheral tolerance and the Th1/Th2 balance. FURIN also promotes the infectivity of pathogens by activating bacteria...
Autores principales: | Cordova, Zuzet Martinez, Grönholm, Anna, Kytölä, Ville, Taverniti, Valentina, Hämäläinen, Sanna, Aittomäki, Saara, Niininen, Wilhelmiina, Junttila, Ilkka, Ylipää, Antti, Nykter, Matti, Pesu, Marko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342350/ https://www.ncbi.nlm.nih.gov/pubmed/27527873 http://dx.doi.org/10.18632/oncotarget.11106 |
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