Importance of the type I insulin-like growth factor receptor in HER2, FGFR2 and MET-unamplified gastric cancer with and without Ras pathway activation

Amplification of seven oncogenes: HER2, EGFR, FGFR1, FGFR2, MET, KRAS and IGF1R has been identified in gastric cancer. The first five are targeted therapeutically in patients with HER2-positivity, FGFR2- or MET-amplification but the majority of patients are triple-negative and require alternative st...

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Detalles Bibliográficos
Autores principales: Saisana, Marina, Griffin, S. Michael, May, Felicity E.B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342354/
https://www.ncbi.nlm.nih.gov/pubmed/27437872
http://dx.doi.org/10.18632/oncotarget.10642

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342354/
https://www.ncbi.nlm.nih.gov/pubmed/27437872
http://dx.doi.org/10.18632/oncotarget.10642

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