Cargando…
Importance of the type I insulin-like growth factor receptor in HER2, FGFR2 and MET-unamplified gastric cancer with and without Ras pathway activation
Amplification of seven oncogenes: HER2, EGFR, FGFR1, FGFR2, MET, KRAS and IGF1R has been identified in gastric cancer. The first five are targeted therapeutically in patients with HER2-positivity, FGFR2- or MET-amplification but the majority of patients are triple-negative and require alternative st...
Autores principales: | Saisana, Marina, Griffin, S. Michael, May, Felicity E.B. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342354/ https://www.ncbi.nlm.nih.gov/pubmed/27437872 http://dx.doi.org/10.18632/oncotarget.10642 |
Ejemplares similares
-
Insulin and the insulin receptor collaborate to promote human gastric cancer
por: Saisana, Marina, et al.
Publicado: (2021) -
HGF-mediated crosstalk between cancer-associated fibroblasts and MET-unamplified gastric cancer cells activates coordinated tumorigenesis and metastasis
por: Ding, Xusheng, et al.
Publicado: (2018) -
HER2, MET and FGFR2 oncogenic driver alterations define distinct molecular segments for
targeted therapies in gastric carcinoma
por: Liu, Y J, et al.
Publicado: (2014) -
Gene amplification of EGFR, HER2, FGFR2 and MET in esophageal squamous cell carcinoma
por: KATO, HIROAKI, et al.
Publicado: (2013) -
Intra-Tumoral Heterogeneity of HER2, FGFR2, cMET and ATM in Gastric Cancer: Optimizing Personalized Healthcare through Innovative Pathological and Statistical Analysis
por: Ye, Peng, et al.
Publicado: (2015)