Crizotinib inhibits NF2-associated schwannoma through inhibition of focal adhesion kinase 1

Neurofibromatosis type 2 (NF2) is a dominantly inherited autosomal disease characterized by schwannomas of the 8th cranial nerve. The NF2 tumor suppressor gene encodes for Merlin, a protein implicated as a suppressor of multiple cellular signaling pathways. To identify potential drug targets in NF2-...

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Detalles Bibliográficos
Autores principales: Troutman, Scott, Moleirinho, Susana, Kota, Smitha, Nettles, Kendall, Fallahi, Mohammad, Johnson, Gary L., Kissil, Joseph L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342359/
https://www.ncbi.nlm.nih.gov/pubmed/27363027
http://dx.doi.org/10.18632/oncotarget.10248

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342359/
https://www.ncbi.nlm.nih.gov/pubmed/27363027
http://dx.doi.org/10.18632/oncotarget.10248

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