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Crizotinib inhibits NF2-associated schwannoma through inhibition of focal adhesion kinase 1

Neurofibromatosis type 2 (NF2) is a dominantly inherited autosomal disease characterized by schwannomas of the 8th cranial nerve. The NF2 tumor suppressor gene encodes for Merlin, a protein implicated as a suppressor of multiple cellular signaling pathways. To identify potential drug targets in NF2-...

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Detalles Bibliográficos
Autores principales:	Troutman, Scott, Moleirinho, Susana, Kota, Smitha, Nettles, Kendall, Fallahi, Mohammad, Johnson, Gary L., Kissil, Joseph L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342359/ https://www.ncbi.nlm.nih.gov/pubmed/27363027 http://dx.doi.org/10.18632/oncotarget.10248

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