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Induction of apoptosis and autophagy via mitochondria- and PI3K/Akt/mTOR-mediated pathways by E. adenophorum in hepatocytes of saanen goat

E. adenophorum has reported to cause hepatotoxicity. But, the precise effects of E. adenophorum on hepatocytes is unclear. Saanen goats were fed on E. adenophorum to detect the cytotoxicity effects of E. adenophorum on hepatocytes. Our study has shown that the typical apoptotic features, the increas...

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Detalles Bibliográficos
Autores principales: He, Yajun, Mo, Quan, Luo, Biao, Qiao, Yan, Xu, Ruiguang, Zuo, Zhicai, Deng, Junliang, Nong, Xiang, Peng, Guangneng, He, Wei, Wei, Yahui, Hu, Yanchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342361/
https://www.ncbi.nlm.nih.gov/pubmed/27391155
http://dx.doi.org/10.18632/oncotarget.10402