Cargando…

Mutation profiling of 19 candidate genes in acute myeloid leukemia suggests significance of DNMT3A mutations

We selected 19 significantly-mutated genes in AMLs, including FLT3, DNMT3A, NPM1, TET2, RUNX1, CEBPA, WT1, IDH1, IDH2, NRAS, ASXL1, SETD2, PTPN11, TP53, KIT, JAK2, KRAS, BRAF and CBL, and performed massively parallel sequencing for 114 patients with acute myeloid leukemias, mainly including those wi...

Descripción completa

Detalles Bibliográficos
Autores principales: Shin, Sang-Yong, Lee, Seung-Tae, Kim, Hee-Jin, Cho, Eun Hae, Kim, Jong-Won, Park, Silvia, Jung, Chul Won, Kim, Sun-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342384/
https://www.ncbi.nlm.nih.gov/pubmed/27359055
http://dx.doi.org/10.18632/oncotarget.10240