Tumor growth accelerated by chemotherapy-induced senescent cells is suppressed by treatment with IL-12 producing cellular vaccines

Standard-of-care chemo- or radio-therapy can induce, besides tumor cell death, also tumor cell senescence. While senescence is considered to be a principal barrier against tumorigenesis, senescent cells can survive in the organism for protracted periods of time and they can promote tumor development...

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Detalles Bibliográficos
Autores principales: Simova, Jana, Sapega, Olena, Imrichova, Terezie, Stepanek, Ivan, Kyjacova, Lenka, Mikyskova, Romana, Indrova, Marie, Bieblova, Jana, Bubenik, Jan, Bartek, Jiri, Hodny, Zdenek, Reinis, Milan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342393/
https://www.ncbi.nlm.nih.gov/pubmed/27448982
http://dx.doi.org/10.18632/oncotarget.10712

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342393/
https://www.ncbi.nlm.nih.gov/pubmed/27448982
http://dx.doi.org/10.18632/oncotarget.10712

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