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Tumor LINE-1 methylation level and colorectal cancer location in relation to patient survival

Colorectal tumors arise with genomic and epigenomic alterations through interactions between neoplastic cells, immune cells, and microbiota that vary along the proximal to distal axis of colorectum. Long interspersed nucleotide element-1 (LINE-1) hypomethylation in colorectal cancer has been associa...

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Detalles Bibliográficos
Autores principales: Mima, Kosuke, Nowak, Jonathan A., Qian, Zhi Rong, Cao, Yin, Song, Mingyang, Masugi, Yohei, Shi, Yan, da Silva, Annacarolina, Gu, Mancang, Li, Wanwan, Hamada, Tsuyoshi, Zhang, Xuehong, Wu, Kana, Meyerhardt, Jeffrey A., Baba, Hideo, Giovannucci, Edward L., Chan, Andrew T., Fuchs, Charles S., Ogino, Shuji, Nishihara, Reiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342404/
https://www.ncbi.nlm.nih.gov/pubmed/27391152
http://dx.doi.org/10.18632/oncotarget.10398