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Tumor LINE-1 methylation level and colorectal cancer location in relation to patient survival
Colorectal tumors arise with genomic and epigenomic alterations through interactions between neoplastic cells, immune cells, and microbiota that vary along the proximal to distal axis of colorectum. Long interspersed nucleotide element-1 (LINE-1) hypomethylation in colorectal cancer has been associa...
Autores principales: | Mima, Kosuke, Nowak, Jonathan A., Qian, Zhi Rong, Cao, Yin, Song, Mingyang, Masugi, Yohei, Shi, Yan, da Silva, Annacarolina, Gu, Mancang, Li, Wanwan, Hamada, Tsuyoshi, Zhang, Xuehong, Wu, Kana, Meyerhardt, Jeffrey A., Baba, Hideo, Giovannucci, Edward L., Chan, Andrew T., Fuchs, Charles S., Ogino, Shuji, Nishihara, Reiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342404/ https://www.ncbi.nlm.nih.gov/pubmed/27391152 http://dx.doi.org/10.18632/oncotarget.10398 |
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