Targeting αvβ3 and αvβ5 integrins inhibits pulmonary metastasis in an intratibial xenograft osteosarcoma mouse model

Osteosarcoma is an aggressive bone cancer that has a high propensity for metastasis to the lungs. Patients with metastatic disease face a very poor prognosis. Therefore, novel therapeutics, efficiently suppressing the metastatic process, are urgently needed. Integrins play a pivotal role in tumor ce...

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Detalles Bibliográficos
Autores principales: Gvozdenovic, Ana, Boro, Aleksandar, Meier, Daniela, Bode-Lesniewska, Beata, Born, Walter, Muff, Roman, Fuchs, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342407/
https://www.ncbi.nlm.nih.gov/pubmed/27409827
http://dx.doi.org/10.18632/oncotarget.10461

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342407/
https://www.ncbi.nlm.nih.gov/pubmed/27409827
http://dx.doi.org/10.18632/oncotarget.10461

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