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High expression of intratumoral stromal proteins is associated with chemotherapy resistance in breast cancer

We studied the changes of intratumoral stromal proteins including THBS1, TNC, FN, SPARC and α-SMA, following neoadjuvant chemotherapy. The underlying mechanisms by which THBS1 and TNC regulated resistance to docetaxel were further studied using functional studies. 100 patients with newly diagnosed b...

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Detalles Bibliográficos
Autores principales: Wang, Tingting, Srivastava, Supriya, Hartman, Mikael, Buhari, Shaik Ahmad, Chan, Ching-Wan, Iau, Philip, Khin, Lay Wai, Wong, Andrea, Tan, Sing-Huang, Goh, Boon-Cher, Lee, Soo-Chin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342408/
https://www.ncbi.nlm.nih.gov/pubmed/27487140
http://dx.doi.org/10.18632/oncotarget.10894