Ranking novel cancer driving synthetic lethal gene pairs using TCGA data

Synthetic lethality (SL) has emerged as a promising approach to cancer therapy. In contrast to the costly and labour-intensive genome-wide siRNA or CRISPR-based human cell line screening approaches, computational approaches to prioritize potential synthetic lethality pairs for further experimental v...

Descripción completa

Detalles Bibliográficos
Autores principales: Ye, Hao, Zhang, Xiuhua, Chen, Yunqin, Liu, Qi, Wei, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342422/
https://www.ncbi.nlm.nih.gov/pubmed/27438146
http://dx.doi.org/10.18632/oncotarget.10536

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342422/
https://www.ncbi.nlm.nih.gov/pubmed/27438146
http://dx.doi.org/10.18632/oncotarget.10536

Ejemplares similares