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Upregulation of brain-derived neurotrophic factor in advanced gastric cancer contributes to bone metastatic osteolysis by inducing long pentraxin 3

The brain-derived neurotrophic factor (BDNF) activates its receptor, tropomyosin receptor kinase B (TrkB; also called NTRK2) that has been shown to promote the malignant progression of several cancers. In this study, we investigated the clinical and biological significance of the BDNF/TrkB axis in t...

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Detalles Bibliográficos
Autores principales: Choi, Bongkun, Lee, Eun-Jin, Shin, Min-Kyung, Park, Young Soo, Ryu, Min-Hee, Kim, Sang-Min, Kim, Eun-Young, Lee, Hyung Keun, Chang, Eun-Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342432/
https://www.ncbi.nlm.nih.gov/pubmed/27458153
http://dx.doi.org/10.18632/oncotarget.10747