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Hypoxia-NOTCH1-SOX2 signaling is important for maintaining cancer stem cells in ovarian cancer
Hypoxia and NOTCH signaling have been reported to be associated with the self-renewal and drug resistance of cancer stem cells (CSCs). However, the molecular mechanisms by which hypoxia and NOTCH signaling stimulate the self-renewal and drug resistance of ovarian CSCs are poorly understood. In the p...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342441/ https://www.ncbi.nlm.nih.gov/pubmed/27489349 http://dx.doi.org/10.18632/oncotarget.10954 |