Fibroblast growth factor 23 dysregulates late sodium current and calcium homeostasis with enhanced arrhythmogenesis in pulmonary vein cardiomyocytes

Fibroblast growth factor 23 (FGF23), elevated in chronic renal failure, increases atrial arrhythmogenesis and dysregulates calcium homeostasis. Late sodium currents (I(Na-Late)) critically induces ectopic activity of pulmoanry vein (the most important atrial fibrillation trigger). This study was to...

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Detalles Bibliográficos
Autores principales: Huang, Shih-Yu, Chen, Yao-Chang, Kao, Yu-Hsun, Hsieh, Ming-Hsiung, Lin, Yung-Kuo, Chung, Cheng-Chih, Lee, Ting-I, Tsai, Wen-Chin, Chen, Shih-Ann, Chen, Yi-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper: Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342473/
https://www.ncbi.nlm.nih.gov/pubmed/27713141
http://dx.doi.org/10.18632/oncotarget.12470

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342473/
https://www.ncbi.nlm.nih.gov/pubmed/27713141
http://dx.doi.org/10.18632/oncotarget.12470

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