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Frequent somatic TERT promoter mutations and CTNNB1 mutations in hepatocellular carcinoma

Genetic alterations of TERT and CTNNB1 have been documented in hepatocellular carcinoma. TERT promoter mutations are the earliest genetic events in the multistep process of hepatocarcinogenesis related to cirrhosis. However, analyses of TERT promoter and CTNNB1 mutations in hepatocellular carcinoma...

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Detalles Bibliográficos
Autores principales: Lee, Seung Eun, Chang, Seong-Hwan, Kim, Wook Youn, Lim, So Dug, Kim, Wan Seop, Hwang, Tea Sook, Han, Hye Seung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342476/
https://www.ncbi.nlm.nih.gov/pubmed/27661004
http://dx.doi.org/10.18632/oncotarget.12121