Pharmacological targeting of BET proteins inhibits renal fibroblast activation and alleviates renal fibrosis

Bromodomain and extra-terminal (BET) protein inhibitors have been shown to effectively inhibit tumorgenesis and ameliorate pulmonary fibrosis by targeting bromodomain proteins that bind acetylated chromatin markers. However, their pharmacological effects in renal fibrosis remain unclear. In this stu...

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Detalles Bibliográficos
Autores principales: Xiong, Chongxiang, Masucci, Monica V., Zhou, Xiaoxu, Liu, Na, Zang, Xiujuan, Tolbert, Evelyn, Zhao, Ting C., Zhuang, Shougang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper: Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342478/
https://www.ncbi.nlm.nih.gov/pubmed/27732564
http://dx.doi.org/10.18632/oncotarget.12498

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342478/
https://www.ncbi.nlm.nih.gov/pubmed/27732564
http://dx.doi.org/10.18632/oncotarget.12498

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