Overexpressed cyclophilin B suppresses aldosterone-induced proximal tubular cell injury both in vitro and in vivo

The renin-angiotensin-aldosterone system (RAAS) is overactivated in patients with chronic kidney disease. Oxidative stress and endoplasmic reticulum stress (ERS) are two major mechanisms responsible for aldosterone-induced kidney injury. Cyclophilin (CYP) B is a chaperone protein that accelerates th...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Bin, Lin, Lilu, Wang, Haidong, Guo, Honglei, Gu, Yong, Ding, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper: Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342479/
https://www.ncbi.nlm.nih.gov/pubmed/27732567
http://dx.doi.org/10.18632/oncotarget.12503

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342479/
https://www.ncbi.nlm.nih.gov/pubmed/27732567
http://dx.doi.org/10.18632/oncotarget.12503

Ejemplares similares