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Overexpressed cyclophilin B suppresses aldosterone-induced proximal tubular cell injury both in vitro and in vivo

The renin-angiotensin-aldosterone system (RAAS) is overactivated in patients with chronic kidney disease. Oxidative stress and endoplasmic reticulum stress (ERS) are two major mechanisms responsible for aldosterone-induced kidney injury. Cyclophilin (CYP) B is a chaperone protein that accelerates th...

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Detalles Bibliográficos
Autores principales:	Wang, Bin, Lin, Lilu, Wang, Haidong, Guo, Honglei, Gu, Yong, Ding, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper: Pathology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342479/ https://www.ncbi.nlm.nih.gov/pubmed/27732567 http://dx.doi.org/10.18632/oncotarget.12503

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