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Implication of NPM1 phosphorylation and preclinical evaluation of the nucleoprotein antagonist N6L in prostate cancer

Despite the advent of several new treatment options over the past years, advanced/metastatic prostate carcinoma (PCa) still remains incurable, which justifies the search for novel targets and therapeutic molecules. Nucleophosmin (NPM1) is a shuttling nucleoprotein involved in tumor growth and its ta...

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Detalles Bibliográficos
Autores principales: Destouches, Damien, Sader, Maha, Terry, Stéphane, Marchand, Charles, Maillé, Pascale, Soyeux, Pascale, Carpentier, Gilles, Semprez, Fannie, Céraline, Jocelyn, Allory, Yves, Courty, José, De La Taille, Alexandre, Vacherot, Francis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342486/
https://www.ncbi.nlm.nih.gov/pubmed/26993766
http://dx.doi.org/10.18632/oncotarget.8043