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Novel regulatory role of neuropilin-1 in endothelial-to-mesenchymal transition and fibrosis in pancreatic ductal adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) is characterized by an intense fibrotic reaction termed tumor desmoplasia, which is in part responsible for its aggressiveness. Endothelial cells have been shown to display cellular plasticity in the form of endothelial-to-mesenchymal transition (EndMT) that s...

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Detalles Bibliográficos
Autores principales: Matkar, Pratiek N., Singh, Krishna Kumar, Rudenko, Dmitriy, Kim, Yu Jin, Kuliszewski, Michael A., Prud'homme, Gerald J., Hedley, David W., Leong-Poi, Howard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342493/
https://www.ncbi.nlm.nih.gov/pubmed/27542226
http://dx.doi.org/10.18632/oncotarget.11060