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Novel regulatory role of neuropilin-1 in endothelial-to-mesenchymal transition and fibrosis in pancreatic ductal adenocarcinoma
Pancreatic ductal adenocarcinoma (PDAC) is characterized by an intense fibrotic reaction termed tumor desmoplasia, which is in part responsible for its aggressiveness. Endothelial cells have been shown to display cellular plasticity in the form of endothelial-to-mesenchymal transition (EndMT) that s...
Autores principales: | Matkar, Pratiek N., Singh, Krishna Kumar, Rudenko, Dmitriy, Kim, Yu Jin, Kuliszewski, Michael A., Prud'homme, Gerald J., Hedley, David W., Leong-Poi, Howard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342493/ https://www.ncbi.nlm.nih.gov/pubmed/27542226 http://dx.doi.org/10.18632/oncotarget.11060 |
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