MXD1 localizes in the nucleolus, binds UBF and impairs rRNA synthesis

MXD1 is a protein that interacts with MAX, to form a repressive transcription factor. MXD1-MAX binds E-boxes. MXD1-MAX antagonizes the transcriptional activity of the MYC oncoprotein in most models. It has been reported that MYC overexpression leads to augmented RNA synthesis and ribosome biogenesis...

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Detalles Bibliográficos
Autores principales: Lafita-Navarro, Maria del Carmen, Blanco, Rosa, Mata-Garrido, Jorge, Liaño-Pons, Judit, Tapia, Olga, García-Gutiérrez, Lucía, García-Alegría, Eva, Berciano, María T., Lafarga, Miguel, León, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342496/
https://www.ncbi.nlm.nih.gov/pubmed/27588501
http://dx.doi.org/10.18632/oncotarget.11766

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342496/
https://www.ncbi.nlm.nih.gov/pubmed/27588501
http://dx.doi.org/10.18632/oncotarget.11766

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