Cargando…
MXD1 localizes in the nucleolus, binds UBF and impairs rRNA synthesis
MXD1 is a protein that interacts with MAX, to form a repressive transcription factor. MXD1-MAX binds E-boxes. MXD1-MAX antagonizes the transcriptional activity of the MYC oncoprotein in most models. It has been reported that MYC overexpression leads to augmented RNA synthesis and ribosome biogenesis...
Autores principales: | Lafita-Navarro, Maria del Carmen, Blanco, Rosa, Mata-Garrido, Jorge, Liaño-Pons, Judit, Tapia, Olga, García-Gutiérrez, Lucía, García-Alegría, Eva, Berciano, María T., Lafarga, Miguel, León, Javier |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342496/ https://www.ncbi.nlm.nih.gov/pubmed/27588501 http://dx.doi.org/10.18632/oncotarget.11766 |
Ejemplares similares
-
Neuronal accumulation of unrepaired DNA in a novel specific chromatin domain: structural, molecular and transcriptional characterization
por: Mata-Garrido, Jorge, et al.
Publicado: (2016) -
SUMO regulates p21(Cip1) intracellular distribution and with p21(Cip1) facilitates multiprotein complex formation in the nucleolus upon DNA damage
por: Brun, Sonia, et al.
Publicado: (2017) -
Persistent accumulation of unrepaired DNA damage in rat cortical neurons: nuclear organization and ChIP-seq analysis of damaged DNA
por: Mata-Garrido, Jorge, et al.
Publicado: (2018) -
Acetylation of UBF changes during the cell cycle and regulates the interaction of UBF with RNA polymerase I
por: Meraner, Joachim, et al.
Publicado: (2006) -
Alternative Splicing of MXD3 and Its Regulation of MXD3 Levels in Glioblastoma
por: Ngo, Tin, et al.
Publicado: (2019)