The dominant-negative interplay between p53, p63 and p73: A family affair

The tumor suppression activity of p53 is frequently impaired in cancers even when a wild-type copy of the gene is still present, suggesting that a dominant-negative effect is exerted by some of p53 mutants and isoforms. p63 and p73, which are related to p53, have also been reported to be subjected t...

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Detalles Bibliográficos
Autores principales: Billant, Olivier, Léon, Alice, Guellec, Solenn Le, Friocourt, Gaëlle, Blondel, Marc, Voisset, Cécile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342497/
https://www.ncbi.nlm.nih.gov/pubmed/27589690
http://dx.doi.org/10.18632/oncotarget.11774

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342497/
https://www.ncbi.nlm.nih.gov/pubmed/27589690
http://dx.doi.org/10.18632/oncotarget.11774

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