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Epigenome-wide association study of smoking and DNA methylation in non-small cell lung neoplasms

Tobacco smoke is a well-established lung cancer carcinogen. We hypothesize that epigenetic processes underlie carcinogenesis. The objective of this study is to examine the effects of smoke exposure on DNA methylation to search for novel susceptibility loci. We obtained epigenome-wide DNA methylation...

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Detalles Bibliográficos
Autores principales: Freeman, Joshua R, Chu, Su, Hsu, Thomas, Huang, Yen-Tsung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342499/
https://www.ncbi.nlm.nih.gov/pubmed/27602958
http://dx.doi.org/10.18632/oncotarget.11831