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DOT1L promotes angiogenesis through cooperative regulation of VEGFR2 with ETS-1

Histone methyltransferase DOT1L is implicated in various biological processes including cell proliferation, differentiation and embryogenesis. Gene ablation of Dot1l results in embryonic lethality and cardiovascular defects including decreased vasculature. However, how DOT1L might contribute to the...

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Detalles Bibliográficos
Autores principales: Duan, Yang, Wu, Xue, Zhao, Qiang, Gao, Jie, Huo, Dawei, Liu, Xinhua, Ye, Zheng, Dong, Xu, Fu, Zheng, Shang, Yongfeng, Xuan, Chenghao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342507/
https://www.ncbi.nlm.nih.gov/pubmed/27626484
http://dx.doi.org/10.18632/oncotarget.11939