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DOT1L promotes angiogenesis through cooperative regulation of VEGFR2 with ETS-1
Histone methyltransferase DOT1L is implicated in various biological processes including cell proliferation, differentiation and embryogenesis. Gene ablation of Dot1l results in embryonic lethality and cardiovascular defects including decreased vasculature. However, how DOT1L might contribute to the...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342507/ https://www.ncbi.nlm.nih.gov/pubmed/27626484 http://dx.doi.org/10.18632/oncotarget.11939 |