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The putative oncotarget CSN5 controls a transcription-uncorrelated p53-mediated autophagy implicated in cancer cell survival under curcumin treatment

Curcumin has shown promise as a safe and specific anticancer agent. The COP9 signalosome (CSN) component CSN5, a known specific target for curcumin, can control p53 stability by increasing its degradation through ubiquitin system. But the correlation of CSN5-controlled p53 to anticancer therapeutic...

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Detalles Bibliográficos
Autores principales: Zhang, Qing-Yu, Jin, Rui, Zhang, Xian, Sheng, Ji-Po, Yu, Fang, Tan, Ren-Xiang, Pan, Ying, Huang, Jun-Jian, Kong, Ling-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342508/
https://www.ncbi.nlm.nih.gov/pubmed/27626169
http://dx.doi.org/10.18632/oncotarget.11940