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Marine compound rhizochalinin shows high in vitro and in vivo efficacy in castration resistant prostate cancer

Development of drug resistance is an inevitable phenomenon in castration-resistant prostate cancer (CRPC) cells requiring novel therapeutic approaches. In this study, efficacy and toxicity of Rhizochalinin (Rhiz) – a novel sphingolipid-like marine compound – was evaluated in prostate cancer models,...

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Detalles Bibliográficos
Autores principales: Dyshlovoy, Sergey A., Otte, Katharina, Alsdorf, Winfried H., Hauschild, Jessica, Lange, Tobias, Venz, Simone, Bauer, Christiane K., Bähring, Robert, Amann, Kerstin, Mandanchi, Ramin, Schumacher, Udo, Schröder-Schwarz, Jennifer, Makarieva, Tatyana N., Guzii, Alla G., Tabakmakher, Kseniya M., Fedorov, Sergey N., Shubina, Larisa K., Kasheverov, Igor E., Ehmke, Heimo, Steuber, Thomas, Stonik, Valentin A., Bokemeyer, Carsten, Honecker, Friedemann, von Amsberg, Gunhild
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342509/
https://www.ncbi.nlm.nih.gov/pubmed/27626485
http://dx.doi.org/10.18632/oncotarget.11941