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Subpathway-LNCE: Identify dysfunctional subpathways competitively regulated by lncRNAs through integrating lncRNA-mRNA expression profile and pathway topologies

Recently, studies have reported that long noncoding RNAs (lncRNAs) can act as modulators of mRNAs through competitively binding to microRNAs (miRNAs) and have relevance to tumorigenesis as well as other diseases. Identify lncRNA competitively regulated subpathway not only can gain insight into the i...

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Detalles Bibliográficos
Autores principales: Shi, Xinrui, Xu, Yanjun, Zhang, Chunlong, Feng, Li, Sun, Zeguo, Han, Junwei, Su, Fei, Zhang, Yunpeng, Li, Chunquan, Li, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342520/
https://www.ncbi.nlm.nih.gov/pubmed/27634882
http://dx.doi.org/10.18632/oncotarget.12005