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Interferon-stimulated gene 15 induces cancer cell death by suppressing the NF-κB signaling pathway

Interferon-stimulated gene 15 (ISG15) is an important cytokine that has been reported in carcinogenesis. However, we found that ISG15 and de-ISGylase USP18 were induced by several anti-cancer agents, which was confirmed by both RT-PCR and immunoblotting assays. Further studies demonstrated that ecto...

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Detalles Bibliográficos
Autores principales: Mao, Hongwu, Wang, Man, Cao, Biyin, Zhou, Haibin, Zhang, Zubin, Mao, Xinliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342541/
https://www.ncbi.nlm.nih.gov/pubmed/27659523
http://dx.doi.org/10.18632/oncotarget.12160