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Interferon-stimulated gene 15 induces cancer cell death by suppressing the NF-κB signaling pathway
Interferon-stimulated gene 15 (ISG15) is an important cytokine that has been reported in carcinogenesis. However, we found that ISG15 and de-ISGylase USP18 were induced by several anti-cancer agents, which was confirmed by both RT-PCR and immunoblotting assays. Further studies demonstrated that ecto...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342541/ https://www.ncbi.nlm.nih.gov/pubmed/27659523 http://dx.doi.org/10.18632/oncotarget.12160 |