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MMP-1 promoter polymorphism is associated with risk of radiation-induced lung injury in lung cancer patients treated with radiotherapy

Matrix metalloproteinase-1 (MMP-1) has been implicated in several inflammatory and fibrotic diseases. We hypothesized that genetic variations in the MMP1 promoter region are associated with risk of radiation-induced lung injury (RILI). A cohort of 251 lung cancer patients was genotyped for five sing...

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Detalles Bibliográficos
Autores principales: Liu, Bo, Yi, Minxiao, Tang, Yang, Liu, Qingxu, Qiu, Hong, Zou, Yanmei, Peng, Ping, Zhang, Lu, Hu, Chunping, Yuan, Xianglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342544/
https://www.ncbi.nlm.nih.gov/pubmed/27659527
http://dx.doi.org/10.18632/oncotarget.12164