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Endothelin-1 promotes epithelial–mesenchymal transition in human chondrosarcoma cells by repressing miR-300

Chondrosarcoma is a malignant tumor of mesenchymal origin predominantly composed of cartilage-producing cells. This type of bone cancer is extremely resistant to radiotherapy and chemotherapy. Surgical resection is the primary treatment, but is often difficult and not always practical for metastatic...

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Detalles Bibliográficos
Autores principales: Wu, Min-Huan, Huang, Pei-Han, Hsieh, Mingli, Tsai, Chun-Hao, Chen, Hsien-Te, Tang, Chih-Hsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342549/
https://www.ncbi.nlm.nih.gov/pubmed/27602960
http://dx.doi.org/10.18632/oncotarget.11835