Pre-existing mutations related to tenofovir in chronic hepatitis B patients with long-term nucleos(t)ide analogue drugs treatment by ultra-deep pyrosequencing

AIMS: The dynamics of resistance-associated mutations under combination therapy were explored. METHODS: A total of 46 patients were classified into adefovir (n=14) and entecavir (n=32) groups. In the adefovir (ADV) group, six patients receiving combined therapy were DNA-positive after more than 3 ye...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaxia, Li, Minran, Xi, Hongli, Zhang, Renwen, Chen, Jianhong, Zhang, Yu, Xu, Xiaoyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342551/
https://www.ncbi.nlm.nih.gov/pubmed/27602500
http://dx.doi.org/10.18632/oncotarget.11840

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342551/
https://www.ncbi.nlm.nih.gov/pubmed/27602500
http://dx.doi.org/10.18632/oncotarget.11840

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