Cargando…
Oncogenic activation of FAK drives apoptosis suppression in a 3D-culture model of breast cancer initiation
A key hallmark of cancer cells is the loss of positional control over growth and survival. Focal adhesion kinase (FAK) is a tyrosine kinase localised at sites of integrin-mediated cell adhesion to the extracellular matrix. FAK controls a number of adhesion-dependent cellular functions, including mig...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342556/ https://www.ncbi.nlm.nih.gov/pubmed/27611942 http://dx.doi.org/10.18632/oncotarget.11856 |