Induction of epithelial-mesenchymal transition (EMT) by Beclin 1 knockdown via posttranscriptional upregulation of ZEB1 in thyroid cancer cells

Beclin 1 has emerged as a haploinsufficient tumor suppression gene in a variety of human carcinomas. In order to clarify the role of Beclin 1 in thyroid cancer, Beclin 1 was knockdown in thyroid cancer cell lines. The current study demonstrated that knockdown of Beclin 1 resulted in morphological an...

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Detalles Bibliográficos
Autores principales: Li, Si, Zhang, Hai-Yan, Du, Zhen-Xian, Li, Chao, An, Ming-Xin, Zong, Zhi-Hong, Liu, Bao-Qin, Wang, Hua-Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342558/
https://www.ncbi.nlm.nih.gov/pubmed/27683118
http://dx.doi.org/10.18632/oncotarget.12217

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342558/
https://www.ncbi.nlm.nih.gov/pubmed/27683118
http://dx.doi.org/10.18632/oncotarget.12217

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