RNF43 and ZNRF3 are commonly altered in serrated pathway colorectal tumorigenesis

Serrated pathway colorectal cancers (CRCs) are characterised by a BRAF mutation and half display microsatellite instability (MSI). The Wnt pathway is commonly upregulated in conventional CRC through APC mutation. By contrast, serrated cancers do not mutate APC. We investigated mutation of the ubiqui...

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Detalles Bibliográficos
Autores principales: Bond, Catherine E., McKeone, Diane M., Kalimutho, Murugan, Bettington, Mark L., Pearson, Sally-Ann, Dumenil, Troy D., Wockner, Leesa F., Burge, Matthew, Leggett, Barbara A., Whitehall, Vicki L.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342576/
https://www.ncbi.nlm.nih.gov/pubmed/27661107
http://dx.doi.org/10.18632/oncotarget.12130

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342576/
https://www.ncbi.nlm.nih.gov/pubmed/27661107
http://dx.doi.org/10.18632/oncotarget.12130

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