miR-135b expression downregulates Ppm1e to activate AMPK signaling and protect osteoblastic cells from dexamethasone

Activation of AMP-activated protein kinase (AMPK) could potently protect osteoblasts/osteoblastic cells from dexamethasone (Dex). We aim to induce AMPK activation via microRNA (“miRNA”) downregulation of its phosphatase Ppm1e. We discovered that microRNA-135b (“miR-135b”) targets the 3' untrans...

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Detalles Bibliográficos
Autores principales: Fan, Jian-Bo, Ruan, Jian-Wei, Liu, Wei, Zhu, Lun-Qing, Zhu, Xin-Hui, Yi, Hong, Cui, Sheng-Yu, Zhao, Jian-Ning, Cui, Zhi-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342578/
https://www.ncbi.nlm.nih.gov/pubmed/27661114
http://dx.doi.org/10.18632/oncotarget.12138

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342578/
https://www.ncbi.nlm.nih.gov/pubmed/27661114
http://dx.doi.org/10.18632/oncotarget.12138

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