Human PDE4D isoform composition is deregulated in primary prostate cancer and indicative for disease progression and development of distant metastases

Phosphodiesterase 4D7 was recently shown to be specifically over-expressed in localized prostate cancer, raising the question as to which regulatory mechanisms are involved and whether other isoforms of this gene family (PDE4D) are affected under the same conditions. We investigated PDE4D isoform co...

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Detalles Bibliográficos
Autores principales: Böttcher, René, Dulla, Kalyan, van Strijp, Dianne, Dits, Natasja, Verhoef, Esther I., Baillie, George S., van Leenders, Geert J.L.H., Houslay, Miles D., Jenster, Guido, Hoffmann, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342582/
https://www.ncbi.nlm.nih.gov/pubmed/27683107
http://dx.doi.org/10.18632/oncotarget.12204

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342582/
https://www.ncbi.nlm.nih.gov/pubmed/27683107
http://dx.doi.org/10.18632/oncotarget.12204

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