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Human PDE4D isoform composition is deregulated in primary prostate cancer and indicative for disease progression and development of distant metastases
Phosphodiesterase 4D7 was recently shown to be specifically over-expressed in localized prostate cancer, raising the question as to which regulatory mechanisms are involved and whether other isoforms of this gene family (PDE4D) are affected under the same conditions. We investigated PDE4D isoform co...
Autores principales: | Böttcher, René, Dulla, Kalyan, van Strijp, Dianne, Dits, Natasja, Verhoef, Esther I., Baillie, George S., van Leenders, Geert J.L.H., Houslay, Miles D., Jenster, Guido, Hoffmann, Ralf |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342582/ https://www.ncbi.nlm.nih.gov/pubmed/27683107 http://dx.doi.org/10.18632/oncotarget.12204 |
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