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ESM1 mediates NGFR-induced invasion and metastasis in murine oral squamous cell carcinoma

Oral squamous cell carcinoma (OSCC) is a highly invasive and metastatic malignancy. The nerve growth factor receptor (NGFR) has been observed to be expressed on a subset of cells in OSCC, and NGFR(+) cells have greater tumor-initiating capacity in vivo. Further, inhibition of NGFR reduces tumor grow...

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Detalles Bibliográficos
Autores principales: Chen, Chen, Shin, June Ho, Eggold, Joshua T., Chung, Man Ki, Zhang, Luhua H., Lee, Jeremy, Sunwoo, John B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342586/
https://www.ncbi.nlm.nih.gov/pubmed/27683113
http://dx.doi.org/10.18632/oncotarget.12210