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Silencing of Profilin-1 suppresses cell adhesion and tumor growth via predicted alterations in integrin and Ca(2+) signaling in T24M-based bladder cancer models
Bladder cancer (BC) is the second most common malignancy of the genitourinary system, characterized by the highest recurrence rate of all cancers. Treatment options are limited; thus a thorough understanding of the underlying molecular mechanisms is needed to guide the discovery of novel therapeutic...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342587/ https://www.ncbi.nlm.nih.gov/pubmed/27683119 http://dx.doi.org/10.18632/oncotarget.12218 |