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Bone marrow involvement identifies a subgroup of advanced Ewing sarcoma patients with fatal outcome irrespective of therapy in contrast to curable patients with multiple bone metastases but unaffected marrow

PURPOSE: Advanced Ewing sarcomas have poor prognosis. They are defined by early relapse (<24 months after diagnosis) and/or by metastasis to multiple bones or bone marrow (BM). We analyzed risk factors, toxicity and survival in advanced Ewing sarcoma patients treated with the MetaEICESS vs. EICES...

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Detalles Bibliográficos
Autores principales: Thiel, Uwe, Wawer, Angela, von Luettichau, Irene, Bender, Hans-Ulrich, Blaeschke, Franziska, Grunewald, Thomas G.P., Steinborn, Marc, Röper, Barbara, Bonig, Halvard, Klingebiel, Thomas, Bader, Peter, Koscielniak, Ewa, Paulussen, Michael, Dirksen, Uta, Juergens, Heribert, Kolb, Hans-Jochem, Burdach, Stefan E.G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342601/
https://www.ncbi.nlm.nih.gov/pubmed/27486822
http://dx.doi.org/10.18632/oncotarget.10938