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7-Ketocholesterol induces ATM/ATR, Chk1/Chk2, PI3K/Akt signalings, cytotoxicity and IL-8 production in endothelial cells

Cardiovascular diseases (atherosclerosis, stroke, myocardiac infarction etc.) are the major systemic diseases of elder peoples in the world. This is possibly due to increased levels of oxidized low-density lipoproteins (oxLDLs) such as 7-ketocholesterol (7-KC) and lysophosphatidylcholine (LPC) that...

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Detalles Bibliográficos
Autores principales: Chang, Mei-Chi, Chen, Yi-Jane, Liou, Eric Jein-Wein, Tseng, Wan-Yu, Chan, Chiu-Po, Lin, Hseuh-Jen, Liao, Wan-Chuen, Chang, Ya-Ching, Jeng, Po-Yuan, Jeng, Jiiang-Huei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342680/
https://www.ncbi.nlm.nih.gov/pubmed/27740938
http://dx.doi.org/10.18632/oncotarget.12578