Cargando…

Rapamycin ameliorates chitosan nanoparticle-induced developmental defects of preimplantation embryos in mice

Chitosan nanoparticles (CSNPs) are used as drug or gene delivery vehicles. However, a detailed understanding of the effects of CSNPs on embryonic development remains obscure. Here, we show that CSNPs can be internalized into mouse blastocysts, such as the zona pellucida, the perivitelline space, and...

Descripción completa

Detalles Bibliográficos
Autores principales: Choi, Yun-Jung, Gurunathan, Sangiliyandi, Kim, DaSom, Jang, Hyung Seok, Park, Woo-Jin, Cho, Ssang-Goo, Park, Chankyu, Song, Hyuk, Seo, Han Geuk, Kim, Jin-Hoi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342693/
https://www.ncbi.nlm.nih.gov/pubmed/27463007
http://dx.doi.org/10.18632/oncotarget.10813