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Rapamycin ameliorates chitosan nanoparticle-induced developmental defects of preimplantation embryos in mice
Chitosan nanoparticles (CSNPs) are used as drug or gene delivery vehicles. However, a detailed understanding of the effects of CSNPs on embryonic development remains obscure. Here, we show that CSNPs can be internalized into mouse blastocysts, such as the zona pellucida, the perivitelline space, and...
Autores principales: | Choi, Yun-Jung, Gurunathan, Sangiliyandi, Kim, DaSom, Jang, Hyung Seok, Park, Woo-Jin, Cho, Ssang-Goo, Park, Chankyu, Song, Hyuk, Seo, Han Geuk, Kim, Jin-Hoi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342693/ https://www.ncbi.nlm.nih.gov/pubmed/27463007 http://dx.doi.org/10.18632/oncotarget.10813 |
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