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Specificity and biologic activities of novel anti-membrane IgM antibodies

The concept that the B-cell Receptor (BCR) initiates a driver pathway in lymphoma-leukemia has been clinically validated. Previously described unique BCR Ig-class-specific sequences (proximal domains (PDs)), are not expressed in serum Ig (sIg). As a consequence of sequence and structural differences...

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Detalles Bibliográficos
Autores principales: Welt, Rachel S., Welt, Jonathan A., Kostyal, David, Gangadharan, Yamuna D, Raymond, Virginia, Welt, Sydney
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342696/
https://www.ncbi.nlm.nih.gov/pubmed/27732950
http://dx.doi.org/10.18632/oncotarget.12506