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Akt isoform specific effects in ovarian cancer progression

Ovarian cancer remains a significant therapeutic problem and novel, effective therapies are needed. Akt is a serine-threonine kinase that is overexpressed in numerous cancers, including ovarian. Mammalian cells express three Akt isoforms which are encoded by distinct genes. Although there are severa...

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Detalles Bibliográficos
Autores principales: Linnerth-Petrik, Nicolle M., Santry, Lisa A., Moorehead, Roger, Jücker, Manfred, Wootton, Sarah K., Petrik, Jim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342704/
https://www.ncbi.nlm.nih.gov/pubmed/27533079
http://dx.doi.org/10.18632/oncotarget.11204