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Zinc enhances temozolomide cytotoxicity in glioblastoma multiforme model systems

Temozolomide (TMZ) is an alkylating agent that has become the mainstay treatment of the most malignant brain cancer, glioblastoma multiforme (GBM). Unfortunately only a limited number of patients positively respond to it. It has been shown that zinc metal reestablishes chemosensitivity but this effe...

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Detalles Bibliográficos
Autores principales: Toren, Amos, Pismenyuk, Tatyana, Yalon, Michal, Freedman, Shani, Simon, Amos J., Fisher, Tamar, Moshe, Itai, Reichardt, Juergen K.V., Constantini, Shlomi, Mardor, Yael, Last, David, Guez, David, Daniels, Dianne, Assoulin, Moria, Mehrian-Shai, Ruty
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342707/
https://www.ncbi.nlm.nih.gov/pubmed/27556862
http://dx.doi.org/10.18632/oncotarget.11382